INVESTIGADORES
FURLAN Ricardo Luis Eugenio
artículos
Título:
Cyclocondensation Versus Cyclocondensation Plus Dehydroxylation During the Reaction of Flavones and Hydrazine
Autor/es:
SOLÍS, CARLOS; SALAZAR, MARIO O.; RAMALLO, I. AYELEN; GARCÍA, PAULA; FURLAN, RICARDO L. E.
Revista:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
WILEY-V C H VERLAG GMBH
Referencias:
Lugar: Weinheim; Año: 2022
ISSN:
1434-193X
Resumen:
Concomitant selective dehydroxylation during the transformation of flavones into pyrazoles with hydrazine is determined by the A-ring substitution pattern and propensity to keto enol tautomerization. The obtained pyrazoles show varied tyrosinase inhibition properties, including one nanomolar inhibitor.
