INVESTIGADORES
FURLAN Ricardo Luis Eugenio
artículos
Título:
Two-stage amplification of receptors using a multilevel orthogonal/simultaneous dynamic combinatorial library
Autor/es:
ESCALANTE, AM; ORRILLO, AG; CABEZUDO, I; FURLAN, RLE
Revista:
ORGANIC LETTERS
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2012 vol. 14 p. 5816 - 5819
ISSN:
1523-7060
Resumen:
Sequential activation of different reversible exchange reactions in a dynamic combinatorial library allows directed exploration of the chemical space: initially a macrocyclic scaffold is selected by the template and finally side chain and conformational constrains are introduced into such scaffold.
