INVESTIGADORES
FURLAN Ricardo Luis Eugenio
artículos
Título:
Detection of antifungal compounds in Polygonum ferrugineum Wedd. extracts by bioassayguided fractionation. Some evidences of their mode of action
Autor/es:
LOPEZ, SN; FURLAN, RLE; ZACCHINO, SA
Revista:
JOURNAL OF ETHNOPHARMACOLOGY
Editorial:
ELSEVIER IRELAND LTD
Referencias:
Lugar: Dublin; Año: 2011 vol. 138 p. 633 - 636
ISSN:
0378-8741
Resumen:
The bioassay-guided fractionation of Polygonum ferrugineum DCM extract allowed the isolation of five active compounds. Among them, cardamonin showed the highest antifungal activity and selectivity towards Epidermophyton floccosum; in addition, it induced Neurospora crassa malformations that are similar than those produced by the crude DCM extract. These results give additional support to the ethnopharmacological use of Polygonum ferrugineum as antifungal agent
