INVESTIGADORES
FERNANDEZ CIRELLI Alicia
artículos
Título:
Simple Stereocontrolled Synthesis of Methyl 2-Deoxy-d-erythro-hexopyranosid-4-uloses, Thromboxane B2 (TXB2) Precursors, from d-Galactose
Autor/es:
O. MORADEI; C. DU MORTIER; A. FERNÁNDEZ CIRELLI; J. THIEM
Revista:
JOURNAL OF CARBOHYDRATE CHEMISTRY
Editorial:
Taylor & Francis
Referencias:
Lugar: Londres; Año: 1995 vol. 14 p. 525 - 532
ISSN:
0732-8303
Resumen:
Abstract
The stereospecific synthesis of methyl 3-O-benzoyl-6-O-(tert-butyldiphenylsilyl)-2-deoxy--d-erythro-hexopyranosid-4-ulose (5) - a Thromboxane B2 (TXB2) precursor -starting from D-galactose is described. Facile and established methods including selective benzoylation, oxidation-elimination and a stereocontrolled hydrogenation (Pd/charcoal) were employed effectively.
