Occurrence of 2-O-sulfated glucuronic acid in highly sulfated heparan sulfates

J. KOVENSKY; A. FERNÁNDEZ CIRELLI

CARBOHYDRATE RESEARCH

Elsevier

Lugar: Amsterdam; Año: 1993 vol. 245 p. 361 - 365

0008-6215

Heparan sulfates are a complex and heterogeneous family of glycosaminoglycans with polysaccharide chain composed of alternating units of  D-glucosamine and uronic acid (D-glucoronic or L-iduronic) with a (1 -->4) linkage. Sulphate substituents occur as N-sulphate (at C-2 of the D-glucosamine residues) or as O-sulphate groups (at C-6 of the D-glucosamine or at C-2 of the L-iudoronic acid units).