INVESTIGADORES
FERNANDEZ CIRELLI Alicia
artículos
Título:
Amine induced deacylation of carbohydrate derivatives under anhydrous conditions
Autor/es:
O. MORADEI; S. LEIT; C. DU MORTIER; A. FERNÁNDEZ CIRELLI; J. THIEM
Revista:
JOURNAL OF CARBOHYDRATE CHEMISTRY
Editorial:
Taylor & Francis
Referencias:
Año: 1993 vol. 12 p. 13 - 22
ISSN:
0732-8303
Resumen:
Methanolysis of acylated carbohydrate derivatives was effectively performed using tertiary amines in the absence of water at room temperature. The reaction was performed with acetylated and benzoylated alditols, aldoses, lactones, orthoesters, glycosides, and disaccharides. N-methyl-pyrrolidine proved to be especially suitable for synthetic purposes and deacylated compounds were obtained in excellent yields. The mild conditions employed and the minimum work-up needed make this method appropriate for the deacylation of labile compounds.
