The help of mathematical modeling in the evaluation of vaccine strategies against pertussis

G. FABRICIUS

Congreso; XII Congreso Latino Americano de Biología Matemática; 2022

In the talk I will make a brief introduction explaining why whooping cough continues to be a public health problem in the world and how mathematical modeling can help to assess the impact of control vaccination strategies. I will comment on the main contributions made by our group to evaluate the impact of vaccination strategies implemented against the disease in Argentina, and also to evaluate the impact of other control measures that we have suggested and could improve the situation [1-3]. [1] Modeling pertussis transmission to evaluate the effectiveness of an adolescent booster in Argentina. G.Fabricius, P.Bergero, M.Ormazabal, A.Maltz and D. Hozbor. Epidemiology and Infection 141, 718-734 (2013). [2] Mathematical modeling of delayed pertussis vaccination in infants. P. Pesco, P.Bergero, G. Fabricius and D. Hozbor. Vaccine 33, 5475-5480 (2015). [3] Pertussis epidemiology in Argentina: trends after the introduction of maternal immunization. G. Fabricius, P. Martin Aispuro P, P. Bergero, M. Gabrielli, D. Bottero, and D.Hozbor. Epidemiology and Infection 146, 858-866 (2018).