Genetic variation in a 9.1-kb insertion/deletion in indigenous and admixed populations from Argentina

DEMARCHI DA, GARCÍA A, ALTUNA ME

HUMAN BIOLOGY

Wayne State University Press

Lugar: Detroit, Michigan, Estados Unidos; Año: 2006 vol. 78 p. 743 - 748

0018-7143

We studied five population samples from Argentina, four drawn from Native American groups of the northeast region (Wichı´, Pilaga´, Toba, and Mbya´-Guaranı´) and one from two small villages of the Co´rdoba province. In this study we report genotypes and allele frequencies of the 9.1-kbinsertion-deletion polymorphism located on chromosome 22. The frequency of the deletion allele ranges from 0.276 in the Mbya´-Guaranı´ to 0.470 in the Pilaga´. The coefficient of population differentiation is fairly low (FST0.013), does not reflect any geographic or linguistic pattern, andseems to be more related to stochastic processes than to directional forces.