Omicron Breakthrough Infection After Heterologous Prime-Boost Vaccination Induces a Vigorous Antibody Response

VARESE, AUGUSTO; MAZZITELLI, BIANCA; ERRA DÍAZ, FERNANDO; KJOLHEDE, MARÍA VICTORIA; OJEDA, DIEGO; VELLICCE, ALEJANDRA; ARTO, PENÉLOPE; CICERO, CARLA; PASCOWSKY, MARÍA; FIGUERAS, LAURA; BROESE, BÁRBARA; DÁVILA, ROSA; ZARLENGA, ROCÍO; RIVELLI, FEDERICO; VERRUNO, CAMILA; SILENZI, VALERIA; BELTRÁN, IVANA; GAMARNIK, ANDREA; CEBALLOS, ANA; ZALA, CARLOS; BADOLATI, ADELINA; GEFFNER, JORGE

The Journal of infectious diseases

NLM (Medline)

Lugar: a; Año: 2022 vol. 226 p. 1717 - 1720

Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is usually asymptomatic or mild and appears to be poorly immunogenic at least in unvaccinated individuals. Here, we found that health care workers vaccinated with 2 doses of Sputnik V and a booster dose of ChAdOx1 mount a vigorous neutralizing-antibody response after Omicron breakthrough infection.