INV SUPERIOR JUBILADO
CASCONE Osvaldo
artículos
Título:
An efficient strategy for preparation of one-bead-one-peptide libraries on a new biocompatible solid support
Autor/es:
S.A. CAMPERI; M.M. MARANI; N.B. IANNUCCI; S. COTE; F. ALBERICIO; O. CASCONE
Revista:
TETRAHEDRON LETTERS
Editorial:
Elsevier
Referencias:
Año: 2005 vol. 46 p. 1561 - 1564
ISSN:
0040-4039
Resumen:
A new strategy for the preparation of one-bead-one-peptide libraries compatible with solid-phase screening and subsequent detachment of the peptide from the resin for sequence determination by MS/MS is described.  The method is based on the use of a ChemMatrix, a new total PEG based resin, together with the 4-hydroxymethylbenzoic acid linker.