INVESTIGADORES
CAMPERI Silvia Andrea
artículos
Título:
Natural Snake Venom inhibitors and their pharmaceutical uses: challenges and possibilities
Autor/es:
SAAVEDRA, SOLEDAD L.; ÁVILA, LUCÍA; GIUDICESSI, SILVANA L.; ALBERICIO, FERNANDO; CAMPERI, SILVIA A.; CASCONE, OSVALDO; MARTINEZ CERON, MARÍA C.
Revista:
CURRENT PHARMACEUTICAL DESIGN.
Editorial:
BENTHAM SCIENCE PUBL LTD
Referencias:
Lugar: Oak Park; Año: 2018 vol. 24 p. 1737 - 1737
ISSN:
1381-6128
Resumen:
Nowadays, treatment with specific antivenins is considered the only cure for snakebites accidents. However, access to antivenom obstructs the successful implementation of the World Health Organization international guidelines. In the last few years, natural organic compounds, peptides and proteins with the ability to inhibit snake toxins and obtained from different sources such as plant extracts and animal blood have been proposed as antivenoms. In this work, we will focus on the inhibitors of the main venom toxins, phospholipases A2 and metalloproteinases, and their application as novel antivenoms.
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