“Comparison between numeric parameters from acute and chronic venous leg ulcers. Identification of potential objective non-healing parameters”.

NICOLAS CERUSICO; ROMINA CHAVES JARA; SILVANA LOPEZ; SILVIA MOLINA; EIGENIA SESTO CABRAL; JUAN CARLOS VALDEZ; AIDA BEN ALTABEF; RAMOS VERNIERI ALBERTO NICOLÁS

Wound Manag Prev.

Woundmanageprevent

Año: 2022 vol. 68

2640-5245

BACKGROUND: Some authors claim that the clinical methods often employed to assess chronic venous leg ulcers (CVLU)are based on subjective interpretation. The treatments based on a subjective characterization could become a trial-and-errortherapy, resulting in longer evolutions and high recurrence rates. PURPOSE: The aim of this work was to compare numericparameters from acute and chronic venous leg ulcers to identify potential objective nonhealing parameters. METHODS: Thestudy was performed with hospital outpatients from 2016 to 2019. Cohorts were established according to the ulcer evolutiontime. Data collected related to ulcer characteristics included exudate pH, lactate and glucose concentrations, temperatures,microbiology fndings, and imaging study results. RESULTS: Approximately 83% of the examined ulcers were chronic. Seventy-one percent of CVLUs and 59% of the acute ulcers had a pH ≥8. A high variability was found for the concentration of glucoseand lactate in exudates of both acute and chronic ulcers. Variations of temperatures of normal skin (ΔT1) and periulcer zone(ΔT2) in reference to the wound bed temperature with values above 1 could indicate the presence of an inflammatory processand be used as a new potential marker of inflammation. All the acute ulcers and 88% of CVLUs showed