Genetic Diversityof GH1 and LEP genes in Argentine llama (Lama glama) populations

MS DAVERIO,Y LORENZO,F RIGALT, L ARBELETCHE VIDAL RIOJA,F DI ROCCO

JOURNAL OF SMALL RUMINANT RESEARCH

ELSEVIER SCIENCE BV

Lugar: Amsterdam; Año: 2014 vol. 120 p. 20 - 26

0921-4488

a b s t r a c tCompared to other domestic species, little is known about variability of genes related toenergetic metabolism and growth in camelids. Here, we have analyzed leptin (LEP) andgrowth hormone (GH1) genes and characterized their variability in three local llama (Lamaglama) populations from the Argentine Northwest. Eleven novel SNPs and one indel wereidentified in the Lep gene. In total, eight haplotypes were found for LEP and seven for GH1.Although geographical origin clustering was not observed, SNP and haplotype frequencies varied significantly among populations. Based on variation of both loci, we detectedsignificant genetic differentiation measured through Fst values.Network analysis of LEP gene supported the well-documented history of hybridizationin camelids previously identified by mtDNA analysis.© 2014 Elsevier B.V. All rights reserved.