Synthesis of macroporous polymer rods based on an acrylamide derivative monomer

RUBEN DARIO ARRUA, CECILIA I. ALVAREZ IGARZABAL, MIRIAM STRUMIA (UNIVERSIDAD NACIONAL DE CÓRDOBA), DANIEL SERRANO Y GUSTAVO PASTRANA (CERÁMICOS ESPECIALES UA TEMADI- CENTRO ATÓMICO BARILOCHE- SAN CARLOS DE BARILOCHE, ARGENTINA)

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Wiley Interscience

Año: 2006 vol. 44 p. 6616 - 6623

0887-624X

New macroporous polymer rods have been prepared by free radical cross-linking copolymerization from N-acryloyl-TRIS(hydroxymethyl)aminomethane (NAT) and N,N´-methylenebisacrylamide (BIS) as cross-linking agent, using different porogenic mixtures and azobisisobutyronitrile (AIBN) as initiator. The porous properties of these materials were controlled by changes in the proportion of the porogenic mixture, polymerization temperature or concentration of cross-linking agent. The pore size distribution profile, shifted towards larger pores size, was obtained in the following cases: when the percentage of co-porogen was increased, when the copolymerization reactions were carried out at low temperature (55ºC), and when the cross-linking concentration used was reduced. Alternatively, a porogenic mixture formed from dimethylsulfoxide (DMSO) and a 1:1 combination of tetradecanol and polyethylenglycol 6000 (PEG 6000) as co-porogens yielded a polymer rod with high porosity and pore size. These hydrophilic materials were promising to be used as base supports for different chromatography processes and as throughput bioreactors.