INVESTIGADORES
AIELLO Ernesto Alejandro
artículos
Título:
The electrogenic Na+/HCO3- cotransport modulates resting membrane potential and action potential duration in cat ventricular myocytes
Autor/es:
MARÍA C. VILLA-ABRILLE; MARTÍN G. VILA PETROFF; ERNESTO A. AIELLO
Revista:
THE JOURNAL OF PHYSIOLOGY
Editorial:
WILEY-BLACKWELL PUBLISHING, INC
Referencias:
Año: 2007 vol. 578 p. 819 - 829
ISSN:
0022-3751
Resumen:
Perforated whole-cell configuration of patch clamp was used to determine the contribution of the electrogenic Na+/HCO3- cotransport (NBC) on the shape of the action potential in cat ventricular myocytes. Switching from HEPES- to HCO3--buffer at constant extracellular pH (pHo) hyperpolarized resting membrane potential (RMP) by 2.67±0.42 mV (n=9, p
