Nitroso Group transfer in nitroso cysteine. Evidences of a new descomposition pathway for nistroso thiols.

C. ADAM, L. GARCÍA-RIO, J-R LEIS AND L. RIBEIRO

Dublin July 4- 8th

Conferencia; Seventh International Conference on Reaction Mechanisms.; 2004

Royal Society of chemistry (RS.C) Organic Reaction Mechanisms Gruoup. Centre for Synthesis and Chemical Biology (CSCB)

Decomposition rate of S-nitrosocysteine within the pH range 0.7<pH<13 shows first and second order with respect to he cysteine concentration. The second order is only observed for pHs between 6.9 and 12. Both first and second order terms show a similar complex dependence with medium acidity: rate increases with pH reaching a maximum around pH=8 and then reaction rate slow down on increasing pH.