INVESTIGADORES
PODEROSO Juan Jose
congresos y reuniones científicas
Título:
Regulación de la respuesta celular a la hipoxia.
Autor/es:
PODEROSO JJ
Lugar:
Mar del Plata, Buenos Aires
Reunión:
Conferencia; LIV Reunión Anual de la SAIC.; 2009
Institución organizadora:
Sociedad Argentina de Investigación Clínica
Resumen:
Mitochondria consume more than 90% of available
oxygen. The physiological pO2 in the mitochondrial
environment is considerably lower than in blood
circulation, and circa 5-10 Torr depending on the different
tissues. However, at that low O2 level, mitochondria still
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
environment is considerably lower than in blood
circulation, and circa 5-10 Torr depending on the different
tissues. However, at that low O2 level, mitochondria still
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
environment is considerably lower than in blood
circulation, and circa 5-10 Torr depending on the different
tissues. However, at that low O2 level, mitochondria still
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
work properly due to the high rate of electron transfer to
O2 by cytochrome oxidase (COX). COX has a very low
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.
Km for oxygen in the 10-7-10-8 M range, and it is regulated by increase of mtNOS.