INVESTIGADORES
CASUSCELLI Sandra Graciela
artículos
Título:
Layered double hydroxides such as an effectively reservoir for Indomethacin and Sodium Indomethacin
Autor/es:
MENDIETA S; NARDÓN E.; PÉREZ C.; CASUSCELLI S; EIMER G.; HERRERO E; MÓNICA CRIVELLO
Revista:
AAPS PHARMSCITECH
Editorial:
SPRINGER
Referencias:
Lugar: Berlin; Año: 2011 p. 795 - 796
ISSN:
1530-9932
Resumen:
Layer double hydroxides (LDH) have been used as catalysts, ion exchangers, adsorbents(1-3). LDH of Mg-Al is biocompatible and has pharmaceutical applications, such as antacids, drug stabilizer, for the therapy of digestive disorders, and others(4). These materials consist of nano-layers of hydroxides, positively charged, and interlayer exchangeable anions. In the present work, Indomethacin (Indo) and Sodium Indomethacin (IndoNa) was incorporated into LDH Mg-Al-Cl by the anionic exchange method.
