IMBECU 20882
INSTITUTO DE MEDICINA Y BIOLOGIA EXPERIMENTAL DE CUYO
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Ischemic postconditioning: role of connexin 43.
Autor/es:
DIEZ ER; RODRÍGUEZ-SINOVAS A; SÁNCHEZ JA; PONCE ZUMINO AZ; GARCÍA-DORADO D
Lugar:
Santiago de Chile
Reunión:
Congreso; XX Meeting ISHR LATIN AMERICAN SECTION; 2012
Institución organizadora:
International Society for Heart Research Latin American Section
Resumen:
Ischemic postconditioning (IP) reduces infarct size and reperfusion arrhythmias. To define the role of connexin 43 (Cx43) in IP protection, we analyzed myocardial electrical resistivity during reperfusion and the influence of Cx43 deficiency on these effects. IP (6 cycles of 10 seconds reperfusion/ischemia) reduced infarct size in isolated mice hearts from wild-type animals after 30 min of global ischemia followed by reperfusion (n=7-9/group, p
