MASked-unconTrolled hypERtension management based on office BP or on ambulatory Blood Pressure measurement (MASTER) Study. A randomised controlled trial protocol

PARATI, G; MANCIA, G; WANG, J; AGABITI-ROSEI, E; MCMANUS, R; BAKRIS, G; RENNA NF

BRITISH MEDICAL JOURNAL

B M J PUBLISHING GROUP

Lugar: Londres; Año: 2018 vol. 12 p. 1 - 10

0959-535X

Introduction: Masked uncontrolled hypertension (MUCH) carries an increased risk ofcardiovascular (CV) complications and can be identified through combined use of office (O) andambulatory (A) blood pressure (BP) monitoring (M) in treated patients. However, it is still debatedwhether the information carried by ABPM should be considered for MUCH management. Aim ofMASTER study is to assess the impact on outcome of MUCH management based on OBPM orABPM. Methods and Analysis. MASTER is a 4-year prospective, randomized, open-label,blinded-endpoint investigation. A total of 1240 treated hypertensive patients from about 40secondary care clinical centers worldwide will be included upon confirming presence of MUCH(repeated on treatment OBP