INVESTIGADORES
ORELLI Liliana Raquel
artículos
Título:
Selective monoformylation of 1,3-diaminopropane derivatives
Autor/es:
LILIANA R. ORELLI; MA. BEATRIZ GARCÍA; FERNANDO NIEMEVZ; ISABEL A. PERILLO
Revista:
SYNTHETIC COMMUNICATIONS
Editorial:
Marcel Dekker
Referencias:
Año: 1999 vol. 11 p. 1819 - 1833
ISSN:
0039-7911
Resumen:
A general procedure for regiospecific construction of N-aryl-N?-formyl- 1,3-diaminopropanes 2 (R=H) by selective monoformylation of N-(3-aminopropy1)arylamines 1 is described. Compounds 1 are readily obtained with high yields by aminolysis of 3-bromopropylamine hydrobromide with aromatic amines. The present synthetic strategy was extended to the synthesis of other Nacyl-N-aryl- 1,3-diaminopropanes
