Expression of GAP-43 in the retina of rats following protracted illumination

LÓPEZ-COSTA JJ, GOLDSTEIN J, MANGEAUD M, SAAVEDRA JP

BRAIN RESEARCH

Elsevier/North-Holland Biomedical Press.

Año: 2001 vol. 900 p. 332 - 336

0006-8993

Distribution of GAP-43 was studied in the retinas of rats after continuous illumination followed by different darkness periods. GAP-43 immunoreactivity was maximum in regenerating outer photoreceptor segments of rats kept in total darkness for 10 days, while in the inner plexiform layer, immunoreactivity was maximum immediately after illumination. Changes in GAP-43 expression could participate in retinal repair/regeneration after light-induced damage.