Dosimetry Optimization System and Integrated Software (DOSIS): a comparison against FLUKA code results over a standard phantom

P. PÉREZ; F. BOTTA; M. CREMONESI; M. FERRARI; F. GUERRIERO; F. MALANO; G. PEDROLI; I. SCARINCI; M. VALENTE

Montevideo

Simposio; X Latin American Symposium on Nuclear Physics and Applications; 2013

Actually, dual-imaging facilities like PET-CT or SPECT-CT allow obtainance of both mass and activity patient-specific distributions perfectly correlated, which are important to improve dose distributions estimations and radioimmunotherapy treatment planifications accuracy.Calculus methods at voxel level require both quantitative and qualitative validation  to obtain improvements in patient-specific  dosimetry. The present work presents advances on the development of a novel  computational tool dedicated to 3D patient-specific dosimetry at voxel level; and its results analysis and visualization.With the aim of providing a dosimetric tool for planar and tridimensional methods at voxel level, as well as the development of a platform based on full-stochastic methods for alpha-, beta- and gamma-emitters used in radiopharmaceutical applications. DOSIS is based on the Boltzmann radiation transport equation to realize energy delivering calculations. Procedures for 2D and 3D dosimetry have been designed tacking into accont established formalism and standars on Pamphlets MIRD 16 and 17 [3]. Anatomic and metabolic images, and dose maps resulting of this calculus are analysed and procesed by a special developed and designed software.DOSIS has been preliminary validated on some standard clinic cases in comparison whith other standard procedures used commonly in radionuclide treatments, showing great accordance on its results and a friendly user usability. Finally, a dose calculation over a standard phantom is performed using DOSIS calculation code and FLUKA, validating the radiation transport code of DOSIS.