Titanium diffusion in shinbone of rats with osseointegrated implants

IBAÑEZ JUAN C; ROBLEDO JOSE; GRENÓN MIRIAM; SÁNCHEZ H. J.

JOURNAL OF MICROSCOPY-OXFORD

WILEY-BLACKWELL PUBLISHING, INC

Lugar: Londres; Año: 2016 vol. 00 p. 1 - 7

0022-2720

SummaryDentalimplantsarecomposedofcommerciallypureTi(which is actually an alloy of titanium, and minor or trace compo- nents such as aluminium and vanadium). When the implant is inserted, its surface undergoes a number of chemical and mechanical processes, releasing particles of titanium to the medium. The metabolism of free ions of titanium is uncer- tain; the uptaking processes in the body are not well known, nor their toxic dose. In addition, physical properties of newly formed bone, such as diffusivity and activation energy, are scarce and rarely studied. In this study, we analysed the dif- fusion of titanium in the titanium-implanted shinbones of six adult male Wistar rats by spatially resolved micro x-ray fluo- rescence.Themeasurementswerecarriedoutatthemicroflu- orescence station of the x-ray fluorescence (XRF) beamline of the Brazilian synchrotron facility LNLS (from Portuguese ?Laboratorio Nacional de Luz Sincrotron?). For each sample, XRF spectra were taken by linear scanning in area near the new bone formed around the Ti implant. The scanning line shows a clear effect of titanium diffusion whereas calcium intensity presents a different behaviour. Moreover, a clear correlation among the different structures of bones is observed in the Ti andCaintensities.Theresultsobtainedinthesemeasurements may allow determining quantitatively the parameters of dif- fusion rates and other physical properties of new bone like diffusion coefficients.