IIIE   20352
INSTITUTO DE INVESTIGACIONES EN INGENIERIA ELECTRICA "ALFREDO DESAGES"
Unidad Ejecutora - UE
artículos
Título:
Eye movements behavior identification for Alzheimer?s disease diagnosis
Autor/es:
BIONDI, JUAN; AGAMENNONI OSVALDO.; FERNANDEZ GERARDO; CASTRO SILVIA
Revista:
JOURNAL OF INTEGRATIVE NEUROSCIENCE
Editorial:
IMPERIAL COLLEGE PRESS
Referencias:
Lugar: London; Año: 2018 vol. 17 p. 349 - 354
ISSN:
0219-6352
Resumen:
We develop a deep-learning approach to differentiate between the eye movement behavior of people with neurodegenerative diseases during reading compared to healthy control subjects. The subjects with and without Alzheimer?s disease read well-defined and previously validated sentences including high- and low-predictable sentences, and proverbs. From these eye-tracking data trial-wise information is derived consisting of descriptors that capture the reading behavior of the subjects. With this information a set of denoising sparse-autoencoders are trained and a deep neural network is built using the trained autoencoders and a softmax classifier that identifies subjects with Alzheimer?s disease with 89.78% accuracy. The results are very encouraging and show that such models promise to be helpful for understanding the dynamics of eye movement behavior and its relation with underlying neuropsychological processes.