INVESTIGADORES
CAPANI Francisco
artículos
Título:
Neuroprotection in Hypoxic-Ischemic Brain Injury Targeting Glial Cells.
Autor/es:
MUCCI S, HERRERA MI, BARRETO GE, KOLLIKER-FRERS R, CAPANI F
Revista:
CURRENT PHARMACEUTICAL DESIGN.
Editorial:
BENTHAM SCIENCE PUBL LTD
Referencias:
Lugar: Oak Park; Año: 2017
ISSN:
1381-6128
Resumen:
Brain injury constitutes a disabling health condition of several etiologies. One of the major causes of brain injury is hypoxia-ischemia. Until recently, pharmacological treatments were solely focused on neurons. In the last decades, glial cells started to be considered as alternative targets for neuroprotection. Novel treatments for hypoxia-ischemia intend to modulate reactive forms of glial cells, and/or potentiate their recovery response. In this review, we summarize these neuroprotective strategies in hypoxia-ischemia and discuss their mechanisms of action.
