Expression based on baculovirus system of properly folded autoantigens -gad65 and ia2ic-involved in autoimmune diabetes mellitus.

TRABUCCHI ALDANA; ROVITTO BRUNO; FACCINETI NATALIA; ALEXANDRA TARGOVNIK; GUERRA LUCIANO; IACONO RUBÉN; EDGARDO POSKUS; MARIA V MIRANDA; SILVINA VALDEZ

Congreso; IV LASID Meeting, LXIII Argentinean Immunology Society Meeting, II French-Argentinean Immunology Meeting.; 2015

The recombinant autoantigens GAD65 and IA2ic were properly expressed in both, SF9 cells and R. nu larvae, holding their immunochemical structure associated to conformational epitopesthat are recognized by diabetic patients? sera.