INVESTIGADORES
FAILLACE Maria Paula
congresos y reuniones científicas
Título:
La retina del pez cebra, génesis y regeneración celular
Autor/es:
FAILLACE MP
Lugar:
Buenos Aires
Reunión:
Seminario; Seminarios IByME- CONICET. Invitada por la Dra. Flavia Saravia; 2011
Institución organizadora:
IBYME-CONICET
Resumen:
We described that injury-induced cell proliferation and death are significantly regulated by extracellular nucleotides mainly acting via P2Y1 receptors in the zebrafish retina. A global damage of the adult zebrafish retina causes an increase and modified distribution of P2Y1 plasma membrane receptors, which are also expressed by proliferative cells. These and complementary findings support extracellular nucleotides and  P2Y1 receptor as key signaling molecules for regulating cell proliferation and death during tissue regeneration as well as normal retinal growth that occur in the adult retina of the zebrafish.