CW Fluorescence imaging of tissue-like media in reflectance geometry

N. CARBONE; D. I. IRIARTE; J. A. POMARICO; DIRK GROSENICK; RAINER MACDONALD

Munich

Conferencia; European Conference on Biomedical Optics (ECBO 2015); 2015

SPIE - OSA

In the present contribution we investigate images of CW diusely remitted light registered by a CCD camera imaging a turbid medium containing an absorbent and uorescent lesion, during illumination by a point-like source. We show that a normalization technique using local background signals reconstructed from experimental data is useful to increase the contrast of both the absorption and the fluorescence channel. Using this technique, results on phantoms are given which demonstrate that lesions with clinically-realistic fluorophore and absorberconcentrations can be detected. Results are compared with theoretical calculations as well.