SEASONAL AFFECTIVE DISORDER AND SMELL (ALTERACIÓN DEL OLFATO EN EL TRASTORNO AFECTIVO ESTACIONAL)

OTERO-LOSADA, M.

Ciudad Autonoma de Buenos Aires

Congreso; VIII Jornadas Multidisciplinarias de la Sociedad Argentina de Biologia; 2006

Sociedad Argentina de Biologia. SAB. IBYME.

The AIM of this work has been to assess smell perception in subjects affected by seasonal depression (SD), on the basis that olfactory denervation unmasks photoperiodic responses in non-photocyclic animals. DISCUSSION: our findings agree with previous evidence indicating lateralization of brain disfunction in SD and suggest that olfaction may be related to seasonal emotional rhythms in humans. Bensafi M, Pierson A, Rouby C, Farget V,Bertrand B, Vigouroux M, Jouvent R, Holley A. Modulation of visual event-related potentials by emotional olfactory stimuli.  Neurophysiol Clin. 2002 Dec;32(6):335-42. Song C, Leonard BE. The olfactory bulbectomised rat as a model of depression. Neurosci Biobehav Rev. 2005; 29 (4-5): 627-647. Goel N, Grasso DJ. Olfactory discrimination and transient mood change in young men and women: variation by season, mood state, and time of day. Chronobiol Int. 2004 Jul;21 (4-5): 691-719. Kruger S., Frasnelli J., Braunig P., Hummel T. Increased olfactory sensitivity in euthymic patients with bipolar disorder with event-related episodes compared with patients with bipolar disorder without such episodes. J Psychiatry Neurosci, July 1, 2006; 31 (4): 263-270.