INVESTIGADORES
GALIGNIANA Mario Daniel
artículos
Título:
Steroid receptor coupling becomes nuclear
Autor/es:
GALIGNIANA MD
Revista:
CHEMISTRY & BIOLOGY
Editorial:
CELL PRESS
Referencias:
Lugar: United States; Año: 2012 vol. 19 p. 662 - 663
ISSN:
1074-5521
Resumen:
In this issue of Chemistry & Biology, Grossman et al. report a study on aldosterone-dependent nuclear translocation of the mineralocorticoid receptor (MR). They analyze the dependency of MR retrotransport, DNA-binding, and transcriptional activity on Hsp90 and demonstrate that MR dimerization is a nuclear event.