Total, Android and Gynoid Fat mass in normal Weight and overweight women

MASTAGLIA SR; SOLIS F; BAGUR A; MAUTALEN CA; OLIVERI B

Toronto

Congreso; Meeting of ASBMR; 2010

ASBMR

Obesity is a world public health problem. It is an independent risk factor for cardiovascular disease and increases morbimortality. Dual X-ray absorptiometry is a valid method to estimate body composition. Objectives: 1-to study a population of women aged 20 to 69 years to obtain normal values for total (TF), android (AF), and gynoid (GF) fat, and android/gynoid coefficient (A/G); 2- to evaluate whether menopause (MP) affects TF, AF, and GF distribution similarly in normal weight and overweight women. Material and Methods: Seventy seven women, average age (X ±DS) 49±14 years (range 20-69 years) and body mass index (BMI) between 18.5-24.9 Kg/m2 and thirty two women, average age 48±12 years with overweight (BMI 25.0-29.9 Kg/m2), were studied. Those receiving hormonal contraceptives, hormone replacement therapy, or medication affecting adipose tissue, or participating in weight loss programs were excluded. TF, GF, AF were determined using a GE Lunar Prodigy densitometer (Encore V 8.1). Statistical analysis (SPSS software) was used to compare pre vs. postmenopause, dividing the population according to BMI. Results: 33 pre-MP (BMI 21±2 Kg/m2) and 44 post-MP (BMI 22±2 Kg/m2) women were normal weight (control group); 13 pre-MP (BMI 26±1 Kg/m2) and 19 post-MP (BMI 27±1Kg/m2) women were overweight. Results are shown in Table (X±DS). During menopause, normal weight women showed changes in TF distribution (18.3±5 vs. 19.6±3 kg, ns) at the expense of AF (1.3±0.5 vs. 1.5±0.5kg, p<0,04) and increase in A/G index (0.7 vs. 0.8, p<0.01). Results showed no significant changes in GF. During menopause, overweight women no exhibited significant changes (GT: 27.6±3 vs. 27.0±4 kg; ns; GA: 2.2±0.5 vs. 2.3±0.5kg; ns, GG: 5.5±0.8kg vs. 5.0±0.8; ns; and A/G:0.9vs.0.9;ns). Conclusion: 1- Fat redistribution during menopause in normal weight women involves greater android fat deposit. 2- Android and gynoid fat deposits increase equally in overweight women. 3- Peripheral conversion to estrogens may contribute to lessening changes in fat compartments in overweight women.