Changes in circulating osteocalcin concentration in overweight and obese adult women having normal glucose and hemoglobin A1c levels

ZENI S.; ZAGO L; GONZALEZ INFANTINO; LUGONES CA; BRITO G; WATSON DZ; OLIVERI B

Congreso; 43ª European Calcified Tissue Society Meeting; 2016

Osteocalcin (OC) plays crucial roles in glucose homeostasis. OC level in the circulation appears to be associated with glucose and fat metabolism ? Although still it remains controversial if it are the levels of total OC and/or undercarboxilated OC (ucOC) which present such association. The present study evaluated the levels of ucOC, total OC, leptin and insulin, in 226 overweight or obese (degree I and II) adult non-diabetic women, having levels of glucose (80?110 mg/dl) and hemoglobin A1c (HbA1c