OLIVERI Maria Beatriz
congresos y reuniones científicas
Persistence of cherubism
FERNANDEZ C; PARISI MS; OLIVERI BEATRIZ
Congreso; XXIII REUNIÓN ANUAL AAOMM; 2007
Cherubism is a rare hereditary disease, characterized by bone degradation and fibrous tissue replacement at the mandible and maxilla. This leads to bilateral expansion of these areas. It´s a self-limiting disease that begins in childhood, progresses until puberty and regresses by middle age. Discussion: a gradual regression of cherubism has been reported until puberty, as a result of the increase in sex hormone levels. The short time of exposition to estrogens in our patient (late age of menarche and early age of menopause), could have been an important cause of absence of disease regression. The impact of reduced bone turnover on bone mineral density and facial lesions must be evaluated.