INVESTIGADORES
SANTA COLOMA Tomas Antonio
artículos
Título:
Characterization of sexual steroid binding protein in Bufo arenarum
Autor/es:
SANTA-COLOMA TA; FERNANDEZ S; CHARREAU EH
Revista:
GENERAL AND COMPARATIVE ENDOCRINOLOGY
Editorial:
ACADEMIC PRESS INC ELSEVIER SCIENCE
Referencias:
Lugar: Amsterdam; Año: 1985 vol. 60 p. 273 - 279
ISSN:
0016-6480
Resumen:
Reproductively active female Bufo arenarum possess a serum protein (SBP) that binds testosterone, dihydrotestosterone, and estradiol with high affinity and capacity. The binding capacity values are two orders of magnitude higher than those found in human serum. The specificity of B. arenarum SBP is comparable to human SBP with the exception that it has a high affinity for the synthetic androgen methyltrienolone (R1881). The physicochemical characterization of SBP indicates a Stokes radius of 43.5 A, a sedimentation coefficient of 5.2 S, and a molecular weight of 93,300.
