Low dietary calcium and obesity: A comparative study in genetically obese and normal rats during early growth: A comparative study in genetically obese and normal rats during early growth.

MAROTE C; BRYK G,; GONZALES CHAVES M; LIFSHITZ F; DE PORTELA ML; ZENI SN

EUROPEAN JOURNAL OF NUTRITION

DR DIETRICH STEINKOPFF VERLAG

Año: 2014 vol. 53 p. 769 - 778

1436-6207

Purpose: A low calcium intake (LCaI) may predispose to obesity and excessive fat mass may be detrimental to bone. Ca inadequacy impact would be greater in subjects predisposed to obesity. LCaI effect on obesity development during a rapid growth period was compared between two strains of rats: spontaneously obese IIMb/b (O) and Wistar (W). Pregnant rats fed 0.5% (N) or 0.2% (L) of Ca (OLCa, ONCa, WLCa and WNCa). Male pups fed the maternal diet until day-60. Methods: Body composition, lipid profile, glucose homeostasis, 25hydroxyvitamin D, Ca-phosphorus and bone metabolisms were evaluated. Results: BW and body fat were higher while body protein was lower in OLCa vs. ONCa (p