Novel pteridine alkaloids from the sponge Clathria sp

ZULETA, I; VITELLI, L.; BAGGIO, R.; GARLAND, M.T.; SELDES, A. M.; PALERMO, J

TETRAHEDRON

Elsevier

Lugar: Amsterdam; Año: 2002 vol. 51 p. 4481 - 4486

0040-4020

Three novel pteridine alkaloids, pseudoanchynazines A – C (1 – 3) have been isolated from the sponge Pseudoanchynoe sp. collected by trawling (-100 m) in a commercial clam fishery near the coasts of Rio Negro, Argentina, and their structures determined by a combination of chemical and spectroscopic techniques, with emphasis in 2D NMR and tandem mass spectrometry. Compounds 1 – 3 have two pteridine units and a tryptophan core with a methyl  carbamate substituent