INVESTIGADORES
MATA Ernesto Gabino
artículos
Título:
Selective detachment of Boc-protected amino acids and peptides from Merrifield, PAM and Wang resins by trimethyltin hydroxide
Autor/es:
FURLÁN, RICARDO L. E.; MATA, ERNESTO G.; MASCARETTI, ORESTE A.; PEÑA, CLARA; COBA, MARCELO P.
Revista:
TETRAHEDRON
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Año: 1998 vol. 54 p. 13023 - 13034
ISSN:
0040-4020
Resumen:
We describe the development of a new non-acidolytic and non- nucleophilic method for the selective cleavage by trimethyltin hydroxide of amino acids and dipeptides at benzyl ester links attached to resins commonly used in peptide synthesis.
