Very efficient and broad-in-scope palladium-catalyzed Hiyama cross-coupling. The role of water and copper(I) salts

TRAFICANTE, CARLA; MATA, ERNESTO G; DELPICCOLO, CARINA M.L.

RSC Advances

ROYAL SOC CHEMISTRY

Lugar: Cambrigde; Año: 2015 vol. 5 p. 26796 - 26800

2046-2069

A very high-yielding Pd-catalyzed cross-coupling between aryl halides and aryl(trialkoxy)silanes is achieved in the presence of Cu(I) and a measured amount of water. This novel methodology is useful for the generation of a wide range of biaryls, particularly non-para substituted derivatives, which are usually less reported