Evaluation of solution and solid phase approaches to the synthesis of libraries of a,a-disubstituted-a-acylaminoketones

J. GARCIA,; ERNESTO G. MATA; C. TICE,; R.E. HORMANN,; E. NICOLAS,; E. MICHELOTTI,; F. ALBERICIO,

J. Comb. Chem.

ACS

Lugar: Washington; Año: 2005 vol. 7 p. 843 - 863

1520-4766

Solid phase, solution and hybrid approaches to the synthesis of small focused libraries of a,a-disubstituted-a-acylaminoketones were explored.  Solution and hybrid approaches that employed support bound reagents and scavenger resins were the most productive.