INVESTIGADORES
GIOVAMBATTISTA Guillermo
artículos
Título:
Association of canine juvenile generalized demodicosis with the dog leucocyte antigen
Autor/es:
IT V.; BARRIENTOS L.; LOPEZ GAPPA J.; POSIK D.M.; DIAZ S.; GOLIJOW C.D.; GIOVAMBATTISTA G.
Revista:
TISSUE ANTIGENS
Editorial:
John Wiley & Sons A/S
Referencias:
Año: 2010 vol. 76 p. 67 - 70
ISSN:
0001-2815
Resumen:
Demodectic mange is a well-known parasitic skin disease characterized by the
presence of a larger than normal number of Demodex mites (Demodex canis) in the
skin of dogs. Recent research has suggested that major histocompatibility complex
(MHC) class II expression is higher in the skin of dogs suffering from demodicosis
than in normal ones. We have investigated whether canine Dog Leukocyte Antigen
(DLA) class II alleles are associated with canine juvenile generalized demodicosis
(JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975
and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed
dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched
controls collected in Argentina were analysed. A highly significant association, in
some of the analysed markers, in all breeds with the presence of demodicosis was
observed with P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
skin of dogs. Recent research has suggested that major histocompatibility complex
(MHC) class II expression is higher in the skin of dogs suffering from demodicosis
than in normal ones. We have investigated whether canine Dog Leukocyte Antigen
(DLA) class II alleles are associated with canine juvenile generalized demodicosis
(JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975
and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed
dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched
controls collected in Argentina were analysed. A highly significant association, in
some of the analysed markers, in all breeds with the presence of demodicosis was
observed with P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
skin of dogs. Recent research has suggested that major histocompatibility complex
(MHC) class II expression is higher in the skin of dogs suffering from demodicosis
than in normal ones. We have investigated whether canine Dog Leukocyte Antigen
(DLA) class II alleles are associated with canine juvenile generalized demodicosis
(JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975
and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed
dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched
controls collected in Argentina were analysed. A highly significant association, in
some of the analysed markers, in all breeds with the presence of demodicosis was
observed with P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
skin of dogs. Recent research has suggested that major histocompatibility complex
(MHC) class II expression is higher in the skin of dogs suffering from demodicosis
than in normal ones. We have investigated whether canine Dog Leukocyte Antigen
(DLA) class II alleles are associated with canine juvenile generalized demodicosis
(JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975
and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed
dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched
controls collected in Argentina were analysed. A highly significant association, in
some of the analysed markers, in all breeds with the presence of demodicosis was
observed with P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
skin of dogs. Recent research has suggested that major histocompatibility complex
(MHC) class II expression is higher in the skin of dogs suffering from demodicosis
than in normal ones. We have investigated whether canine Dog Leukocyte Antigen
(DLA) class II alleles are associated with canine juvenile generalized demodicosis
(JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975
and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed
dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched
controls collected in Argentina were analysed. A highly significant association, in
some of the analysed markers, in all breeds with the presence of demodicosis was
observed with P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
skin of dogs. Recent research has suggested that major histocompatibility complex
(MHC) class II expression is higher in the skin of dogs suffering from demodicosis
than in normal ones. We have investigated whether canine Dog Leukocyte Antigen
(DLA) class II alleles are associated with canine juvenile generalized demodicosis
(JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975
and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed
dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched
controls collected in Argentina were analysed. A highly significant association, in
some of the analysed markers, in all breeds with the presence of demodicosis was
observed with P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
Demodex canis) in the
skin of dogs. Recent research has suggested that major histocompatibility complex
(MHC) class II expression is higher in the skin of dogs suffering from demodicosis
than in normal ones. We have investigated whether canine Dog Leukocyte Antigen
(DLA) class II alleles are associated with canine juvenile generalized demodicosis
(JGD). In the present study, the analysis of microsatellite markers (FH2202, FH2975
and FH2054) linked to DLA was made in Boxer, Argentinean Mastiff and mixed breed
dogs. DNA samples from 56 dogs affected with the disease and 60 breed-matched
controls collected in Argentina were analysed. A highly significant association, in
some of the analysed markers, in all breeds with the presence of demodicosis was
observed with P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.
P < 0.05 and odds ratio (OR) ¡Ý5. The results of this study suggest
that an underlying DLA association exists with demodicosis in dogs and that this may
represent an important immunological risk factor in the aetiology of this condition.
This information could be used in the future to develop diagnostic tests to prevent
canine JGD.