Functionalized magnetite nanoparticles. Study of its physicochemical properties and biocompatible applications.

LAGORIO, M. GABRIELA; MARCHI, MARIA CLAUDIA; TORRES, ROCIO; DIZ, VIRGINIA E.

Ljubljana

Workshop; 7th ISGS Online Summer School; 2020

International Sol-Gel Society (ISGS)

Functionalized magnetite nanoparticles. Study of its physicochemicalproperties and biocompatible applications. Rocio Torres[1,2], Maria Gabriela Lagorio [1,2], Maria Claudia Marchi [1,3], VirginiaEmilse Diz [2][1] CONICET,Universidad de Buenos Aires, INQUIMAE, Facultad de Ciencias Exactas yNaturales, Buenos Aires, Argentina[2] Universidad deBuenos Aires, Facultad de Ciencias Exactas y Naturales, Dpto. de QuímicaInorgánica, Analítica y Química Física, Ciudad Universitaria. Pabellón II, 1erpiso, C1428EHA, Buenos Aires, Argentina[3] Centro deMicroscopias Avanzadas (CMA), Facultad de Ciencias Exactas y Naturales,Departamento de Física, Ciudad Universitaria, Pabellón I, C1428EHA, BuenosAires, Argentina. Nanoparticles ofmagnetite (NPs-Fe3O4) are incredibly versatile systems with multipleapplications in science and technology.[1] Surface modification of magnetic NPswith organic molecules presents many advantages as low cost of production,physicochemical stability, biocompatibility, safe to the environment and easycoating [2]. This NPs have been the subject of an enormous scientificproduction in the last decade, and numerous biological applications have beenreported. In this work, Fe3O4 with different coatings were used in multipleapplications as adsorption of various pollutants, effluent remediation,bacteria capture and plant fertilization. NPs-Fe3O4 of 11 nm of diameter weresynthesized with several coatings such as amino acids (arginine and cysteine) ,oxalate, polyethylene glycol and humic-acids. Its physicochemical propertieswere examined from electron microscopy, X-ray diffraction, infraredspectroscopy, magnetization, Z potential, among others. From thecharacterization of the material size homogeneity, high magnetization, presenceof the coatings could be confirmed from the characteristic signals in theinfrared, surface charge strongly dependent on the coating, high synthesisyield and surface area. Subsequently, heavy metal adsorption tests such as As,Pb, Cu, Hg were carried out with high removal efficiencies greater than thosecurrently reported in bibliography. The bacteria capture efficiency was 95-97%[3] and the combination of dolomite and magnetic nanoparticles were highlyefficient for the removal of phosphates and chromates in effluents. Likewise,the nanoparticles were shown to possess fertilizer characteristics byincreasing the photosynthesis efficiency in leaves sprayed with nanoparticles.We believe that synthesized and functionalized nanoparticles have highpotential for biomedical and agricultural applications and for the adsorptionof pollutants and bacteria. However, although the results presented here arepromising, more studies are necessary to determine their applicability.  [1] W. Wu, Z.Wu, T. Yu, C. Jiang, W.S. Kim, Recent progress on magnetic iron oxidenanoparticles: Synthesis, surface functional strategies and biomedicalapplications, Sci. Technol. Adv. Mater. 16 (2015) 23501. https://doi.org/10.1088/1468-6996/16/2/023501. [2] A.H. Lu,E.L. Salabas, F. Schüth, Magnetic nanoparticles: Synthesis, protection,functionalization, and application, Angew. Chemie - Int. Ed. 46 (2007)1222?1244. https://doi.org/10.1002/anie.200602866. [3] F.Figueredo, A. Saavedra, E. Cortón, V. Diz, Hydrophobic Forces Are Relevant toBacteria-Nanoparticle Interactions: Pseudomonas putida Capture Efficiency byUsing Arginine, Cysteine or Oxalate Wrapped Magnetic Nanoparticles, Colloidsand Interfaces. 2 (2018) 29. https://doi.org/10.3390/colloids2030029.