INSTITUTO DE QUIMICA, FISICA DE LOS MATERIALES, MEDIOAMBIENTE Y ENERGIA
Unidad Ejecutora - UE
Mass transport effect of mesoscopic domains in the amperometric
GRACIELA GONZÁLEZ, GRACIELA PRIANO, MAURICIO GÜNTHER, FERNANDO BATTAGLINI
SENSORS AND ACTUATORS B-CHEMICAL
We report the numerical simulation of an electrochemical system compromising a mesoporous material placed at a close distance of a working electrode. The effect of mesoscopic domains to the amperometric response of an electroactive species by applying a cyclic voltammetry is simulated to establish the in.uence of different parameters on the sensitivity of this system to detect molecules able to block the pores. Alumina membranes were chosen as mesoporous material; they were modi.ed with antihorseradish peroxidase as model system to test the behavior predicted by the simulation. The label-free assembled electrochemical system shows a reproducible behavior and it is able to detect a 10 nMprotein concentration.