Molecular interaction sensors: A new type of detector for separation methods.

LUC J. NAGELS; JOSEPH EVERAERT; BERT VISSERS; JUSTYNA SEKULA; HUGO BOHETS; MARIA MONGE; KARL PEETERS; NICO VERVOORT; KAMILLA SADOWSKA; DOMINIKA KOZIOWSKA; MARCUS BREWSTER; KOEN VANHOUTTE

LC•GC Europe

Advanstar Communications

Año: 2007 vol. 20 p. 558 - 566

Potentiometry is a new detection method for liquid chromatography (LC) and capillary electrophoresis (CE). The principle behind this method is familiar to chromatographers because the signals depend on the partitioning tendency of analytes over the sensor coating and the eluent. This partitioning provokes a change in the surface potential and the detection of these changes can be classified as "potentiometric". A conversion algorithm is needed to convert the generated signals to concentration-related tracings(chromatograms).