UMYMFOR 05516
UNIDAD DE MICROANALISIS Y METODOS FISICOS EN QUIMICA ORGANICA
Unidad Ejecutora - UE
artículos
Título:
Synthesis and characterization of a new polyaminocarboxylic macrocyclic ligand and its non-ion gadolinium complex. in vitro relaxivity studies at 0.2 T
Autor/es:
MARIO DAVID MARTINEZ; EDUARNO MIGUEL RUSTOY; NORBERTO RAGGIO; GERARDO BURTON
Revista:
INORGANIC CHEMISTRY COMMUNICATIONS
Editorial:
ELSEVIER SCIENCE BV
Referencias:
Lugar: Amsterdam; Año: 2014 vol. 51 p. 110 - 113
ISSN:
1387-7003
Resumen:
In this study a novel ligand with three carboxylic groups (H3L1) was synthesized. Its non-ion complex with GdL1 holding promise of magnetic resonance imaging (MRI) was synthesized, and the relaxivity of the complex determined. The relaxivity of GdL1 (R1 = 4.5 Mmol- 1·s- 1) was larger than that of Gd(DTPA)2 -(R1 = 3.9 Mmol- 1·s- 1). The results showed that the non-ion complex is a prospective MRI contrast agent.
