UMYMFOR 05516
UNIDAD DE MICROANALISIS Y METODOS FISICOS EN QUIMICA ORGANICA
Unidad Ejecutora - UE
artículos
Título:
Dolabellane Diterpenoids from the South Atlantic Gorgonian Convexella magelhaenica.
Autor/es:
MARÍA TEREZA ROJO DE ALMEIDA, GASTÓN E. SILESS, CARLOS D. PEREZ, MARÍA JOSÉ VELOSO, LAURA SCHEJTER, LYDIA PURICELLI, JORGE A. PALERMO
Revista:
JOURNAL OF NATURAL PRODUCTS
Editorial:
AMER CHEMICAL SOC
Referencias:
Año: 2010 p. 1714 - 1717
ISSN:
0163-3864
Resumen:
Two new dolabellane diterpenoids (1-2) were isolated from a small sample of the deep water gorgonian octocoral Convexella magelhaenica collected as a non-target by-catch by dredging (-93 m) in a commercial Patagonian scallop fishing ground in the South Atlantic. The structures of the new compounds, which are major metabolites in the extract, were established by spectroscopic techniques and chemical transformations. Both compounds were cytotoxic against a human pancreatic adenocarcinoma cell line at micromolar concentrations.
