IFIBYNE   05513
INSTITUTO DE FISIOLOGIA, BIOLOGIA MOLECULAR Y NEUROCIENCIAS
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Dopamine modulates appetitive memory in two arthropods
Autor/es:
KLAPPEBACH MARTIN; FERNANDO LOCATELLI
Lugar:
Santiago de Chile
Reunión:
Workshop; Small Brains, Big Ideas; 2012
Institución organizadora:
Faculty of Medicine - Universidad de Chile
Resumen:
Robust
learning paradigms and relatively simple nervous systems with access for
diverse experimental techniques convert invertebrates into powerful models for
studying the cellular basis of learning and memory. Pathways that encode the
conditioned and unconditioned stimuli and the brain areas of sensory
integration have been mapped in Drosophila and honey bees. It has been
demonstrated that two monoamines, dopamine and octopamine mediate aversive and
appetitive reinforcements respectively. Even though it was initially understood
that DA exclusively mediates aversive learning and octopamine is the
counterpart for appetitive learning, more recent works indicate that both
amines may interact during learning. Here we present our results in two
arthropods, crabs and honey bees, which suggest that dopamine negatively
modulates appetitive long-term memory formation.