INDIVIDUAL BEHAVIORAL DIFFERENCES AND PRENATAL ETHANOL EXPOSURE PREDICT ETHANOL INTAKE DURING ADOLESCENCE

PAUTASSI RM

Sao Paulo

Conferencia; Ciclo de Conferencias del Instituto de Ciências Biomédicas; 2013

UNIVERSIDADE DO SAO PAULO / INSTITUTO DE CIENCIAS BIOMEDICAS

Aims of the Talk: To describe differences in sensitivity to ethanol between adolescent and adults that may explain the higher propensity of adolescent to engage into problematic alcohol intake. 2: To describe behavioral differences among adolescents that may help identify those particularly susceptible to problematic alcohol intake. 3: To analyze the effects of even earlier experiences with alcohol (i.e., infancy or gestation, on alcohol intake. Concluding Remaks: The adolescent pattern of reactivity to ethanol and stress seems to put them at risk for escalating into problematic alcohol intake. 2: Among adolescents, those exhibiting greater response to novelty, greater response to ethanol stimulating effects and greater baseline anxiety might be more prone to drink the drug. 3: Prenatal ethanol exposure significantly predicts later ethanol intake, an effect seems to be driven by a KOR-related increase in the rewarding effects of ethanol. 4: These results pinpoint early markers for exacerbated alcohol intake that could be used to target subjects at risk for alcohol use disorders.