CONICET | Buscador de Institutos y Recursos Humanos

: Topical administration is preferred for ocular drug delivery to the structures of the front part of the eye, such as the cornea and the conjunctiva. Traditional ocular topical dosage forms have limitations in solving many eye diseases. The main reason could be attributed to the rapid and extensive drainage loss of the formulation in the precorneal area as a result of blinking and tear replacement. A promising alternative to increasing the residence time of formulations in the area of application is the use of bioadhesive systems capable of releasing controlled amounts of the desired drug.