Anionic Ring Opening Polymerization of epsilon-Caprolactone for Siloxane-Caprolactone Block Copolymer

A.J. SATTI; F. NADOR; E. M. VALLÉS

Granada

Congreso; European Polymer Congress: EPF 2011, XII GEP Congreso; 2011

ICTP-CSIC EPF

Poly(ƒÕ-caprolactone) (PCL) is a biodegradable polyester which can be used as drug carrier because of its excellent drug permeability. Poly(dimethylsiloxane) (PDMS) is a biocompatible hydrophobic polymer with good properties as surface modifier. This combination makes PDMS-based copolymers excellent candidates for several biomedical applications. Thus, many synthetic strategies have been developed in order to synthesize block copolymers of siloxane/ƒÕƒ{caprolactone for specific applications. In this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). biodegradable polyester which can be used as drug carrier because of its excellent drug permeability. Poly(dimethylsiloxane) (PDMS) is a biocompatible hydrophobic polymer with good properties as surface modifier. This combination makes PDMS-based copolymers excellent candidates for several biomedical applications. Thus, many synthetic strategies have been developed in order to synthesize block copolymers of siloxane/ƒÕƒ{caprolactone for specific applications. In this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). biodegradable polyester which can be used as drug carrier because of its excellent drug permeability. Poly(dimethylsiloxane) (PDMS) is a biocompatible hydrophobic polymer with good properties as surface modifier. This combination makes PDMS-based copolymers excellent candidates for several biomedical applications. Thus, many synthetic strategies have been developed in order to synthesize block copolymers of siloxane/ƒÕƒ{caprolactone for specific applications. In this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). biodegradable polyester which can be used as drug carrier because of its excellent drug permeability. Poly(dimethylsiloxane) (PDMS) is a biocompatible hydrophobic polymer with good properties as surface modifier. This combination makes PDMS-based copolymers excellent candidates for several biomedical applications. Thus, many synthetic strategies have been developed in order to synthesize block copolymers of siloxane/ƒÕƒ{caprolactone for specific applications. In this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). ƒÕ-caprolactone) (PCL) is a biodegradable polyester which can be used as drug carrier because of its excellent drug permeability. Poly(dimethylsiloxane) (PDMS) is a biocompatible hydrophobic polymer with good properties as surface modifier. This combination makes PDMS-based copolymers excellent candidates for several biomedical applications. Thus, many synthetic strategies have been developed in order to synthesize block copolymers of siloxane/ƒÕƒ{caprolactone for specific applications. In this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL). ƒÕƒ{caprolactone for specific applications. In this work, we report the synthesis of these block copolymers under different reaction conditions by using anionic polymerization. We explored the use of PDMS macroinitiators to promote the anionic ring opening polymerization (AROP) of e-caprolactone (e-CL).-caprolactone (e-CL).